Chlamydophila infection in cats can be treated very effectively with antibiotics. Systemic antibiotics are more effective than local treatment [Sparkes et al, 1999]. Tetracyclines are generally regarded as the antibiotics of choice for chlamydial infections [Dean et al 2005]. Doxycycline has the advantage of requiring only a single daily dose and is most frequently used at a dosage of 10 mg/kg orally. Recent studies have shown that treatment must be maintained for 4 weeks to ensure elimination of the organism [Dean et al 2005]. In some cats recrudescence may be noted some time after discontinuation of therapy. Continuation of treatment for two weeks after resolution of clinical signs is recommended. Tetracyclines have potential side effects in young cats although these appear to be less common with doxycycline than oxytetracycline. Alternative antibiotics may be considered if this is a concern. Fluoroquninolones are effective against Chlamydia [Gerhardt et al., 2007; Hartmann et al., 2008], but a 4-week course of therapy with clavulanic acid potentiated amoxicillin may represent the safest choice in young kittens [Sturgess et al, 2001].